Friday, February 21, 2020

Apple's Adaptation to Global, Economic and Social Changes Since 1990 Essay

Apple's Adaptation to Global, Economic and Social Changes Since 1990 - Essay Example Steve Jobs came back again as the interim Chief Executive Officer , he laid down the strategies and the goals systemically and started off by building the Macintosh franchise and made an addition of an operating system which was developed at Next Inc. ‘Apple, the Silicon Valley company that has become an icon of personal computing, rose to its greatest heights in the years after Mr. Jobs returned to its helm and opened horizons beyond the desktop.’ (Apple Incorporated (AAPL) News - Company Information - The New York Times) ‘Rather than growing Apple share, as originally planned , cloners instead took Mac sales away from Apple. Next , Jobs created the machines that would save Apple, the iMac’(O'GRADY, J. D., Apple Inc 2009). ‘Apple needed experienced leadership if it was going to grow as rapidly as called in the business plan.’(LINZMAYER, O. W., & LINZMAYER, O. W, Apple confidential 2.0 2004) The revolution took place in the music industry with t he introduction of the iPod music player , and changed the course of the consumer electronics in the favour of Apple. And the market share increased even more when the iTunes Music Store was launched which assisted the users in filling their iPods with their favourite songs(Apple Incorporated (AAPL) News - Company Information - The New York Times). ... rporated (AAPL) News - Company Information - The New York Times) The global economic crisis was not successful in affecting the strong position of the company and within a matter of few years , Apple was declared as the largest company of the world in terms of the market capitalization and announced as the entity which had the most liquid assets.( U.S. balance now less than Apple cash | Financial Post) What made Apple the market leader was the introduction of the smart phones, for which it has now become the market leader. Currently in the smart phone industry, Apple is enjoying the record breaking sales revenue and the profits , showing that the entity adapted very well to the technological advancements in the world. It has become the conqueror of this industry. ‘Apple had an amazing impact on the technology, society and the world. And it continues to innovate to this day’ (O'GRADY, J. D., Apple Inc 2009). Furthermore, the success of the smart phones pushed the entity t o consider the idea of a tablet device which was rejected by Jobs back in 2005. iPad was another fine contribution made by Apple, making the entity the pioneer in the tablets industry. Recently Apple introduced the third generation tablet for which it is already reporting the record breaking sales. ‘Apple also said iPad users had downloaded more than one million apps from the company’s App Store and more than 250,000 electronic books from its iBookstore.’ (Apple Incorporated (AAPL) News - Company Information - The New York Times) ‘Apple is sitting just about as close to the top of the world as possible right now. The world’s most valuable company, it’s got a market capitalization flirting again with the $500 billion mark, and even a flash crash in morning trading on Monday didn’t bring

Wednesday, February 5, 2020

Myocardial Infarction Research Paper Example | Topics and Well Written Essays - 1750 words

Myocardial Infarction - Research Paper Example The area deprived of blood supply is said to have suffered ischemic injury. The ischemic injury, if severe enough to cause the complete block of oxygen and nutrients causes death of the heart tissue, which is termed as Myocardial Infarction (Guyton et al 200, Ganong 2005). Pathophysiology The blood vessels supplying the heart are called coronary arteries. There are three main coronary arteries which supply different areas of heart along with their branches. These are 1) Right coronary artery, 2) Left anterior descending artery, 3) Left circumflex artery. Above 90% cases of myocardial infarction occur as a result of coronary artery blockage, thus the disease is also referred to as coronary artery disease (CAD). The most common and dangerous cause of coronary artery obstruction, and thus MI is Atherosclerosis. Atherosclerosis refers to the narrowing of arteries because of accumulation of atherosclerotic plaques. These plaques are basically thrombi composed of lipid foam cells (choleste rol) and different cell components including smooth muscle, macrophages and collagen fibres. In most instances, the ischemic myocardial infarction is precipitated by the phenomenon called acute plaque change. Acute plaque change results from the rupture of pre-existing thrombi that partially occlude the lumen. The rupture exposes the underlying thrombogenic endothelium. The plaques are also termed as vulnerable plaques as they contain lipids in high amounts, along with collagen fibres and inflammatory cells. When ruptured, the reactivity of these components causes the inflammatory destabilization and result in the infarction (Libby P 2001). The acute phase reactant, C reactive protein (CRP) is thus found to be high during the acute myocardial infarction (Blake et al 2003). The infarction can occur in either of the two patterns, complete occlusion of a single coronary artery referred to as transmural infarct, which results in complete ischemia of the area supplied by that particular coronary artery. Subendocardial infarcts on the other hand occlude the arteries incompletely, and thus allow some perfusion. But since subendocardium is the least perused area of the myocardium, it is more prone to ischemic death. The aim of reperfusion is to save the viable muscle from necrosis (Huber et al 1996). The myocardial injury is reversible for up to 30 minutes after the ischemic attack, thereafter the injury becomes irreversible. The entire muscle becomes necrotic within six hours, if the collateral arteries are not well developed (Robbins et al 2005, Mohan 2007). Etiology of Myocardial Infarction The development of atherosclerotic plaques and pathogenesis of the process into the myocardial infarction is a complex one. It is a chronic disease taking years to evolve before it causes any modifiable consequences. The evolvement is subtle and the resultant damage is severe. The pathogenesis of the disease involves several factors. The balance among these factors in the long r un determines the outcome of the condition. These factors can either be modifiable or non-modifiable. The modifiable factors are the ones that a person can control by bringing about certain changes. They include controlling the level of fats in diet, cessation of smoking, regular exercise and maintaining the blood pressure in the normal range (Manson et al 1996). The hyperlipidemias, i.e. elevated low density